When will I see results from under-eye polynucleotides?

Early improvements can appear within the first few weeks, with clearer results building over 2–3 months as collagen and elastin production increases.

Do polynucleotides give immediate volume like fillers?

No. Polynucleotides work through skin regeneration, not immediate plumping. They gradually improve hydration, texture and firmness over time.

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How long do polynucleotides last under the eyes?

Q: How long do polynucleotides last under the eyes?

After a full course of 2–3 sessions, polynucleotide results under the eyes typically last between 6 to 9 months. Maintenance top-up treatments are recommended every 6–9 months depending on skin condition and lifestyle factors.

After completing a full course of polynucleotides (usually 2–3 sessions), the under-eye results typically last 6 to 9 months. This varies based on age, lifestyle, hydration, skin quality and how consistently you maintain treatments.

What affects longevity?

Age & skin condition — healthier skin often holds results for longer.
Number of sessions — completing all sessions gives better durability.
Maintenance — top-ups every 6–9 months help sustain the benefits.
Lifestyle — smoking, stress, sun exposure and poor sleep affect collagen levels.

What results can you expect?

Polynucleotides work by improving the skin’s natural structure, not by adding volume. This means the improvements are gradual and look very natural.

Early changes: subtle improvements within a few weeks.
Best results: usually after 2–3 months once collagen and hydration increase.
Side effects: mild swelling or redness can occur but usually settles within days.
No instant plumping: unlike fillers, polynucleotides improve the skin over time.

Learn more about treatment: Polynucleotides →