How many polynucleotide sessions do I need?
Most people need 2–3 sessions of polynucleotides to achieve healthy, long-lasting skin improvement. At Dermamina, we recommend a 3-session course spaced 3–4 weeks apart, as this supports collagen production, tissue repair and hydration in a gradual, natural way.
Initial Course (Induction Phase)
Polynucleotides work by stimulating your skin’s natural healing and repair process — not by adding instant filler volume. Because regeneration takes time, a course of sessions helps the benefits build steadily.
- 2–3 sessions total (Dermamina recommends 3 for best results)
- Spaced 3–4 weeks apart
- Gradual improvement as collagen, elastin and hydration increase
- Visible brightening and smoothing develops across several weeks
Maintenance Sessions
After completing your initial course, a maintenance session every 6 months helps keep results fresh and long-lasting.
- Top-ups every 6 months
- Frequency varies depending on age, skin health and lifestyle
- Helps preserve improved texture, glow and firmness
Why multiple sessions?
Polynucleotides activate fibroblasts, hydration pathways and tissue repair. Because this is a natural biological process, each session builds on the last. Most clients notice:
- More glow and hydration within a few weeks
- Smoother texture and reduced fine lines over 6–12 weeks
- Stronger, healthier-looking skin across 3–6 months
Next Step
To start your personalised plan, visit the main Polynucleotides Treatment page to book your consultation.
